Brdu Monoclonal Antibody | E-AB-70248

Brdu Monoclonal Antibody | E-AB-70248 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: Bromodeoxyuridine;Bromodeoxyuridine;5-Bromo-2′-deoxyuridine; 5-BrdU; Proliferation Marker; 5-Bromo-2-deoxyUridine.

Application: IHC, IF

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Cell Biology, Neuroscience, Tags and Cell Markers, Epigenetics and Nuclear Signaling

Background: Bromodeoxyuridine (5-bromo-2'-deoxyuridine, BrdU, BUdR, BrdUrd) is a synthetic nucleoside that is an analog of thymidine. It can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. As such, BrdU is used for birth dating and monitoring cell proliferation. BrdU is a toxic and mutagenic substance. It triggers cell death, the formation of teratomas, alters DNA stability, lengthens the cell cycle, and has mitogenic, transcriptional and translational effects on cells that incorporate it. 

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated BrdU

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:100-1:500, IF 1:100-1:500

Clone: 4B6C12

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A