Brivanib Alaninate | B1326

Brivanib Alaninate is an ATP-competitive inhibitor of VEGFR2 with (IC₅₀ = 25 nM). Displays potent antineoplastic activity.

Brivanib Alaninate is an ATP-competitive inhibitor of VEGFR2 with (IC₅₀ = 25 nM). Displays potent antineoplastic activity.

B1326 | Brivanib Alaninate DataSheet

Alternate Name/Synonyms: [(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate; BMS-582664

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 649735-63-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₄FN₅O₄

Molecular Weight: 441.46

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>40 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: ATP-competitive inhibitor of VEGFR2 with anticancer properties

MDL Number: N/A

PubChem CID: 11154925

SMILES: CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)OC(=O)C(C)N)C

InChi: InChI=1S/C22H24FN5O4/c1-11-7-15-16(27-11)5-6-17(19(15)23)32-21-20-13(3)18(8-28(20)26-10-25-21)30-9-12(2)31-22(29)14(4)24/h5-8,10,12,14,27H,9,24H2,1-4H3/t12-,14+/m1/s1

InChi Key: LTEJRLHKIYCEOX-OCCSQVGLSA-N