Bromodomain Testis-specific Protein (BrdT), human recombinant | 7641

BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. ’s recombinant protein includes Bromo 1 domain (22-138 aa) with N-terminal His-tag.

7641 | Bromodomain Testis-specific Protein BrdT human recombinant DataSheet

Biomolecule/Target: BRDT

Synonyms: Recombinant Human Bromodomain Testis-specific Protein (BrdT)

Alternates names: BCMA, CD269, Tumor Necrosis Factor Receptor Superfamily Member 17, BCM, TNFRSF17, B-cell maturation protein, CD269 antigen.

Taglines: A protein driving meiotic and post-meiotic gene expression program

NCBI Gene ID #: 608

NCBI Gene Symbol: TNR17

Gene Source: Human

Accession #: Q02223

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 5.3 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.

Reconstitution Instructions: It is recommended to reconstitute the lyophilized BCMA in sterile dHO not less than 100 g/ml, which can then be further diluted to other aqueous solutions.

Amino acid sequence: N/A