BRWD1 Antibody | 14-565

BRWD1 Antibody | 14-565 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human BRWD1 (NP_001007247.1) .

Research Area: Other

Tested Application: WB

Application: WB: 1:1000 - 1:3000

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: Jurkat

Positive Control 3: SGC-7901

Positive Control 4: NIH/3T3

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 263kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: bromodomain and WD repeat domain containing 1, bromodomain and WD repeat-containing protein 1, BRWD1, C21orf107, FLJ43918, N143, OTTHUMP00000068796, OTTHUMP00000068797, OTTHUMP00000068928, OTTHUMP00000207967, transcriptional unit N143, WD repeat protein WDR9-form2, WD repeat-containing protein 9, WDR9, WDR9

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.