BSCL2 Antibody | 15-615

BSCL2 Antibody | 15-615 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse, Rat

Homology: N/A

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human BSCL2 (NP_116056.3) .

Research Area: Neuroscience, Obesity

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: Mouse brain

Positive Control 2: Mouse lung

Positive Control 3: Mouse testis

Positive Control 4: Rat brain

Positive Control 5: Rat testis

Positive Control 6: N/A

Molecular Weight: Observed: 46kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: GNG3LG, HMN5, PELD, SPG17, seipin, BSCL2, seipin lipid droplet biogenesis associated, Berardinelli-Seip congenital lipodystrophy 2 (seipin) , Bernardinelli-Seip congenital lipodystrophy type 2 protein

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2) .