BTBD1 Antibody (Center) [APR11013G]

BTBD1 Antibody (Center) [APR11013G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This BTBD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the Central region of human BTBD1.

Cellular Localisation: Cytoplasm. Note=Localizes to punctate or elongated cytoplasmic bodies.

Molecular Weight: 52771

Clone: Polyclonal

Gene Name: BTBD1

Gene ID: 53339

Function: Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312) . Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism (By similarity) . May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis (By similarity) .

Summary: Tissue Location: Ubiquitous; highest levels in testes, heart and skeletal muscle.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: BTB/POZ domain-containing protein 1, Hepatitis C virus NS5A-transactivated protein 8, HCV NS5A-transactivated protein 8, BTBD1, C15orf1, NS5ATP8