BTBD17 Polyclonal Antibody | BS65427

BTBD17 Polyclonal Antibody | BS65427 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Sheep,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD17 (BTB/POZ domain-containing protein 17), also known as BTBD17A, galectin-3-binding protein-like or LGALS3BPL, is a 478 amino acid protein that contains one BTB (POZ) domain and a BACK (BTB/Kelch associated) domain. The gene encoding BTBD17 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: BTBD17 Polyclonal Antibody detects endogenous levels of BTBD17 protein.

Molecular Weight: 49kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BTB/POZ domain-containing protein 17; btbd17; BTBDH_HUMAN; Galectin-3-binding protein-like.

Immunogen: KLH conjugated synthetic peptide derived from human BTBD17:101-200/478

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: