BTC, human recombinant | 4876

Human Betacellulin (BTC) is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the egf receptor and other related receptors. Human Recombinant BTC produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and having a molecular mass of 9 kDa. BTC was purified by proprietary chromatographic techniques.

4876 | BTC human recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: Betacellulin, BTC

Alternates names: Beta-defensin 3, Defensin, beta 103, Defensin-like protein, DEFB103A, BD3, DEFB103, DEFB3, DEFB103B

Taglines: A ligand for the EGF receptor

NCBI Gene ID #: 140596

NCBI Gene Symbol: DEFB4

Gene Source: Human

Accession #: Q8WTQ1

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 97%

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-50 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: ~6.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized after extensive dialysis against 20 mM phosphate buffer, pH 7.4.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile dd HO to a concentration 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 2-7 days and at -20 °C for future use.

Amino acid sequence: N/A