BTK Antibody [9D11A9] | 13-186

BTK Antibody [9D11A9] | 13-186 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant protein of human BTK

Research Area: Apoptosis, Cell Cycle, Immunology, Innate Immunity, Signal Transduction

Tested Application: WB, IP

Application: WB: 1:500 - 1:2000
IP: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: K-562

Positive Control 2: Raji

Positive Control 3: THP-1

Positive Control 4: Mouse spleen

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 80kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Monoclonal

Clone: [9D11A9]

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: BTK Antibody: AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1, Tyrosine-protein kinase BTK, Agammaglobulinemia tyrosine kinase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.