BTK Polyclonal Antibody | E-AB-64314

BTK Polyclonal Antibody | E-AB-64314 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA, BTK

Application: WB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology, Signal Transduction

Background: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human BTK (NP_000052.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 76 kDa/79 kDa

Molecular Weight(Observed): 76 kDa