BTZ043 | B1206

BTZ043 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis (TB). It displays nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.

BTZ043 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis (TB). It displays nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.

B1206 | BTZ043 DataSheet

Alternate Name/Synonyms: (S)-2-(2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1161233-85-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₆F₃N₃O₅S

Molecular Weight: 431.39

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A decaprenyl-phosphoribose-epimerase (DprE1) inhibitor

MDL Number: N/A

PubChem CID: 42609849

SMILES: CC1COC2(O1)CCN(CC2)C3=NC(=O)C4=CC(=CC(=C4S3)[N+](=O)[O-])C(F)(F)F

InChi: InChI=1S/C17H16F3N3O5S/c1-9-8-27-16(28-9)2-4-22(5-3-16)15-21-14(24)11-6-10(17(18,19)20)7-12(23(25)26)13(11)29-15/h6-7,9H,2-5,8H2,1H3/t9-/m0/s1

InChi Key: GTUIRORNXIOHQR-VIFPVBQESA-N