Bu-1a Antibody [21-1A4] (PE) | 99-293

Bu-1a Antibody [21-1A4] (PE) | 99-293 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Chicken

Homology: N/A

Immunogen: Bursa cells from one-day-old H.B15 (Bu-1a/b) strain chickens

Research Area: Other

Tested Application: Flow

Application: Bu-1a Antibody [21-1A4] for use in flow cytometry assays.

Specificiy: Bu-1a

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [21-1A4]

Isotype: IgG1

Conjugate: PE

Physical State: Liquid

Buffer: Supplied in PBS/NaN3 and a stabilizing agent

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: ChB6.1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Chicken Bu-1a, a product of the Bu-1a allele, is expressed on the cell surface as a disulfide-linked homodimer. In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. In chickens heterozygous for the Bu-1 alleles (Bu-1a/b) , Bu-1a does not exhibit allelic exclusion. The monoclonal antibody 21-1A4 does not react with cells from CHA and H.B14ab strains by immunofluorescence.