BuB1B (BubR1) monoclonal Antibody | MB62648

BuB1B (BubR1) monoclonal Antibody | MB62648 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Rat, Dog

Application: FC, IF, WB

Application Range: WB 1:500~2000, IF 1:100, FLOW 1:100

Background: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: BUB1 mitotic checkpoint serine/threonine kinase B

Molecular Weight: 119.3 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1

Immunogen: Full length human recombinant protein of human BUB1B (NP_001202) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A