c-Kit Antibody [kit2c75] | 99-298

c-Kit Antibody [kit2c75] | 99-298 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Chicken

Homology: N/A

Immunogen: Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA)

Research Area: Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

Tested Application: IHC-Fr, ICC, Flow, IP

Application: c-Kit Antibody [kit2c75] for use in flow cytometry assays.

Specificiy: c-Kit

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [kit2c75]

Isotype: IgG2a

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: CD117

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: c-Kit is a 145 kDa transmembrane receptor-type protein tyrosine kinase encoded by the c-Kit proto-oncogene and is the receptor for stem cell factor (SCF) . c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis, and adhesion. The amino acid sequence of chicken c-kit shows 63% identity to mouse c-Kit and exhibits similar expression patterns in RNA blot analysis suggesting similar biological roles.