Additional Information
Size: |
100 µl |
Target: |
c-Met (pTyr1349) |
Conjugate: |
PE/ATTO 594 |
Research Area: |
Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | Receptor Tyrosine Kinases | Cancer | Tumor Biomarkers | Oncoproteins | Growth Factor Receptors | Cell Signaling | Epigenetics and Nuclear Signaling | Transcription |
Alternative Name: |
MET Antibody, Proto-oncogene c-Met Antibody, Met proto-oncogene (hepatocyte growth factor receptor) Antibody, HGF/SF receptor Antibody, AUTS9 Antibody, D249 Antibody, Oncogene MET Antibody, Met protooncogene Antibody, Par4 Antibody, MET proto oncogen |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic phospho-peptide from human c-Met around the phosphorylation site of tyrosine 1349 (pTyr1349). |
Immunogen Species: |
Human |
Applications: |
WB |
Host: |
Rabbit |
Isotype: |
IgG |
Species Reactivity: |
Human, Mouse, Rat |
Antibody Dilution: |
WB (1:250-1:1000); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide |
Concentration: |
N/A |
Specificity: |
Detects endogenous levels of c-Met only when phosphorylated at tyrosine 1349 (pTyr1349). Detects a band at ~145 kDa. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
N/A |
Cellular Localization: |
Membrane, Single-Pass Type I Membrane Protein, Secreted, Extracellular Region, Plasma Membrane, Basal Plasma Membrane, Integral Component Of Plasma Membrane, Cell Surface, Integral Component Of Membrane, Intracellular |
Tissue Specificity: |
Expressed in normal hepatocytes as well as in epithelial cells lining the stomach, the small and the large intestine. Found also in basal keratinocytes of esophagus and skin. High levels are found in liver, gastrointestinal tract, thyroid and kidney. |
Accession Number: |
NP_000236.2 |
Gene ID: |
4233 |
Swiss-Prot: |
P08581 |
Field of Use: |
For in vitro research use only. |