C11orf30 Antibody (N-term) [APR32702G]

C11orf30 Antibody (N-term) [APR32702G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human C11orf30.

Cellular Localisation: Nucleus. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process

Molecular Weight: 141468

Clone: Polyclonal

Gene Name: EMSY (HGNC:18071)

Gene ID: 56946

Function: Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin (PubMed:14651845) . Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 (PubMed:14651845) . Mediates ligand-dependent transcriptional activation by nuclear hormone receptors (PubMed:19131338) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Protein EMSY, EMSY, C11orf30