C14orf179 Antibody (Center) [APR15189G]

C14orf179 Antibody (Center) [APR15189G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This C14orf179 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human C14orf179.

Cellular Localisation: Cytoplasm, cytoskeleton. Cell projection, cilium Note=Associated with microtubules (PubMed:22361696) . Localized at the distal tip of the cilium (PubMed:28973684)

Molecular Weight: 23529

Clone: Polyclonal

Gene Name: IFT43 (HGNC:29669)

Gene ID: 112752

Function: As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in ciliogenesis (PubMed:28400947, PubMed:28973684) . Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base (PubMed:21378380) .

Summary: Tissue Location: Expressed in the retina, predominantly in the photoreceptor outer segment.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Intraflagellar transport protein 43 homolog, IFT43, C14orf179