C1orf186 Antibody (C-term) [APR32219G]

C1orf186 Antibody (C-term) [APR32219G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This C1orf186 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the C-terminal region of human C1orf186.

Cellular Localisation: Cell membrane; Single-pass membrane protein

Molecular Weight: 19405

Clone: Polyclonal

Gene Name: RHEX (HGNC:25341)

Gene ID: 440712

Function: Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation (PubMed:25092874) .

Summary: Tissue Location: Expressed in the proerythroblasts (at protein level) (PubMed:25092874) . Expressed strongly in the kidney (PubMed:25092874) . Expressed weakly in the pancreas, liver and lung (PubMed:25092874) . Expressed strongly in erythroid progenitor cells (EPCs) (PubMed:25092874) . Expressed weakly in T-cells and neutrophils (PubMed:25092874) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Uncharacterized protein C1orf186, C1orf186