CA6 polyclonal Antibody | BS5637

CA6 polyclonal Antibody | BS5637 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB ICC

Application Range: WB: 1:500~1:1000 ICC: 1:50~1:200

Background: Carbonic anhydrase VI (CA VI) contributes to taste function when secreted in the saliva by protecting taste receptor cells (TRCs) from apoptosis. Functional CA VI exists as a single polypeptide chain tightly bound to one molecule of zinc, and containing two N-linked glycosylation sites. Decreased CA VI secretion correlates with loss of taste (hypogeusia) and smell (hyposmia) or distorted taste (dysgeusia) and smell (dysosmia), and altered taste bud morphology. Addition of zinc to individuals experiencing these symptoms restored secretion of CA VI to normal levels and normal taste bud morphology in some, but not all, cases, indicating two different mechanisms leading to CA VI dysfunction.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CA6 polyclonal Antibody detects endogenous levels of Carbonic anhydrase 6 protein.

Molecular Weight: ~ 37 kDa (glycosylated) ~ 33 kDa (deglycosylated)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Carbonic anhydrase 6; Carbonic anhydrase6; Carbonate dehydratase VI; Carbonic anhydrase VI; CA-VI; Salivary carbonic anhydrase; Secreted carbonic anhydrase; CA-6

Immunogen: Synthetic peptide, corresponding to the 263-308 of Human CA6.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A