CABLES1 Antibody | 13-587

CABLES1 Antibody | 13-587 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CABLES1 (NP_612384.1) .

Research Area: Cell Cycle

Tested Application: WB, IHC

Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: MCF7

Positive Control 2: HT-29

Positive Control 3: A-549

Positive Control 4: HL-60

Positive Control 5: HeLa

Positive Control 6: Mouse brain

Molecular Weight: Observed: 67kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CABL1, CABLES, HsT2563, IK3-1, CDK5 and ABL1 enzyme substrate 1, interactor with CDK3 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127) .Multiple transcript variants encoding different isoforms have been found for this gene.