CACNA1F Antibody (Center) [AMM05662G]

CACNA1F Antibody (Center) [AMM05662G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CACNA1F antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 743-776 amino acids from the Central region of human CACNA1F.

Cellular Localisation: Membrane; Multi-pass membrane protein.

Molecular Weight: 220678

Clone: Polyclonal

Gene Name: CACNA1F (HGNC:1393)

Gene ID: 778

Function: [Isoform 1]: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Activates at more negative voltages and does not undergo calcium- dependent inactivation (CDI), due to incoming calcium ions, during depolarization.

Summary: Tissue Location: Expression in skeletal muscle and retina (PubMed:10873387) . Isoform 4 is expressed in retina (PubMed:27226626)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Voltage-dependent L-type calcium channel subunit alpha-1F, Voltage-gated calcium channel subunit alpha Cav14, CACNA1F, CACNAF1