Description
CACNA2D3 Antibody | 13-574 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 900-1040 of human CACNA2D3 (NP_060868.2) .
Research Area: Neuroscience, Signal Transduction
Tested Application: WB
Application: WB: 1:1000 - 1:2000
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: HeLa
Positive Control 3: HepG2
Positive Control 4: Mouse brain
Positive Control 5: Rat brain
Positive Control 6: N/A
Molecular Weight: Observed: 123kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Voltage-dependent calcium channel subunit alpha-2/delta-3, Voltage-gated calcium channel subunit alpha-2/delta-3, Voltage-dependent calcium channel subunit alpha-2-3, Voltage-dependent calcium channel subunit delta-3, CACNA2D3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.