CADD522 | B2731

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC₅₀ of 10 nM. CADD522 treatment results in significant growth inhibition, clonogenic survival, and invasion of breast cancer cells

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC₅₀ of 10 nM. CADD522 treatment results in significant growth inhibition, clonogenic survival, and invasion of breast cancer cells

B2731 | CADD522 DataSheet

Alternate Name/Synonyms: 3-((3,4-dichlorophenyl)carbamoyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid,CADD-522

Appearance: Crystalline solid

Formulation:

CAS Number: 199735-88-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₃Cl₂NO₃

Molecular Weight: 326.17

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >50 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding

MDL Number:

PubChem CID: 2834870

SMILES: C1C2C=CC1C(C2C(=O)NC3=CC(=C(C=C3)Cl)Cl)C(=O)O

InChi: InChI=1S/C15H13Cl2NO3/c16-10-4-3-9(6-11(10)17)18-14(19)12-7-1-2-8(5-7)13(12)15(20)21/h1-4,6-8,12-13H,5H2,(H,18,19)(H,20,21)

InChi Key: YSDNWNOGHQYWPK-UHFFFAOYSA-N