Cadherin-18 (Q129) polyclonal Antibody | BS2222

Cadherin-18 (Q129) polyclonal Antibody | BS2222 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Cadherin-18 (Q129) polyclonal Antibody detects endogenous levels of Cadherin-18 protein.

Molecular Weight: ~ 88 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cadherin 18; Cadherin-14; CDH18; CDH14; Cadherin18; Cadherin 14; Cadherin14

Immunogen: Synthetic peptide, corresponding to amino acids 96-140 of Human Cadherin-18.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A