cADP-Ribose, ammonium salt | B2656

Cyclic ADP-ribose (cADP-ribose) is potent calcium (Ca ²⁺) second messenger. This endogenous metabolite of NAD+ mobilizes the release of stored Ca²⁺ in the endoplasmic reticulum via ryanodine receptors in various cell types.

yclic ADP-ribose (cADP-ribose) is potent calcium (Ca ²⁺) second messenger. This endogenous metabolite of NAD+ mobilizes the release of stored Ca²⁺ in the endoplasmic reticulum via ryanodine receptors in various cell types.

B2656 | cADP-Ribose, ammonium salt DataSheet

Alternate Name/Synonyms: cADP-Ribose; 1-β-D-ribofuranosyl-adenosine 5'-(trihydrogen diphosphate), intramol. P',5''-ester, diammonium salt; cADPR

Appearance: White solid

Formulation:

CAS Number: 119340-53-3 (Free base)

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: Ammonium salt

Molecular Formula: C₁₅H₁₉N₅O₁₃P₂• 2NH₄

Molecular Weight: 575.4

Cell-Permeable?: True

Purity: ~90%

Solubilities: in Water

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent calcium second messenger

MDL Number:

PubChem CID: 123847

SMILES: N=C1C2=C(N3C=N2)N=CN1[C@@]4([H])[C@H](O)[C@H](O)[C@](COP(OP(OC[C@@]5([H])O[C@]3([H])[C@H](O)[C@@H]5O)([O-])=O)([O-])=O)([H])O4.[NH4+].[NH4+]

InChi: InChI=1S/C15H21N5O13P2.2H3N/c16-12-7-13-18-4-19(12)14-10(23)8(21)5(31-14)1-29-34(25,26)33-35(27,28)30-2-6-9(22)11(24)15(32-6)20(13)3-17-7;;/h3-6,8-11,14-16,21-24H,1-2H2,(H,25,26)(H,27,28);2*1H3/t5-,6-,8-,9-,10-,11-,14-,15-;;/m1../s1

InChi Key: IGYAJGYAGRVAJM-SPJXZGHLSA-N