Caffeine | 2914

Caffeine is a popular central nervous system (CNS) stimulant. It is a well-studied substrate of Cytochrome P450 enzymes like CYP1A2. Caffeine is taken up by transporters at the blood brain barrier. Its stimulating effects are believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. It can affect cellular calcium levels, releasing calcium from cellular stores. It has been shown to inhibit cellular DNA repair mechanisms.

Caffeine is a substrate of Cytochrome P450 enzymes like CYP1A2. Caffeine is taken up by transporters at the blood brain barrier. It is an adenosine receptor antagonist and adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase inhibitor.

2914 | Caffeine DataSheet

Alternate Name/Synonyms: 1,3,7-trimethylxanthine, Methyltheobromine, 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Appearance: White powder

Formulation: N/A

CAS Number: 58-08-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₈H₁₀N₄O₂

Molecular Weight: 194.2

Cell-Permeable?: Yes

Purity: ≥99% by HPLC

Solubilities: Water (~16 mg/ml), Ethanol (~15 mg/ml)

Handling: Protect from air, light and moisture

Country of Origin: USA

Tag Line: A substrate of Cytochrome P450 1A2

MDL Number: MFCD00005758

PubChem CID: 2519

SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2C)C

InChi: InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChi Key: RYYVLZVUVIJVGH-UHFFFAOYSA-N