Calcitriol | 1880

An active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Plays important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. It has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Known to act as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds.

Calcitriol is an active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Plays important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. It has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function.

1880 | Calcitriol DataSheet

Alternate Name/Synonyms: 1α, 25-Dihydroxycholecalciferol; 1a,25-Dihydroxyvitamin D3; 25-(OH)2-D3

Appearance: White solid

Formulation: N/A

CAS Number: 32222-06-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₇H₄₄O₃

Molecular Weight: 416.64

Cell-Permeable?: No

Purity: ≥99% by HPLC

Solubilities: DMSO (50 mg/ml) or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An activator of the vitamin D receptor (VDR)

MDL Number: MFCD00867079

PubChem CID: 5280453

SMILES: CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C

InChi: InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23, 24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1

InChi Key: GMRQFYUYWCNGIN-NKMMMXOESA-N