CALCRL Antibody (Center) [APR15224G]

CALCRL Antibody (Center) [APR15224G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CALCRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-367 amino acids from the Central region of human CALCRL.

Cellular Localisation: Cell membrane; Multi-pass membrane protein

Molecular Weight: 52929

Clone: Polyclonal

Gene Name: CALCRL

Gene ID: 10203

Function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity) . Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739) . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:22102369, PubMed:30115739) .

Summary: Tissue Location: Predominantly expressed in the lung and heart.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P-Leica, WB

Dilution: WB--1:2000

Synonyms: Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor, CALCRL, CGRPR