Caldesmon (Ab-759) polyclonal Antibody | BS65240

Caldesmon (Ab-759) polyclonal Antibody | BS65240 | Gentaur UK, US & Europe Distribution

Host: Mouse/IgG2b, Kappa

Reactivity: Human

Application: IHC-p,IF (paraffin section)

Application Range: IHC-p 1:100-500，WB 1:500-2000

Background: caldesmon 1 (CALD1) Homo sapiens This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+) -calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) -dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of human Caldesmon. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section

Molecular Weight: /

Note: For

Alternative Names: N/A

Immunogen: Synthesized peptide derived from human Caldesmon

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pathway: