Calreticulin monoclonal Antibody | MB9108

Calreticulin monoclonal Antibody | MB9108 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Application: WB IHC ICC FC

Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: Calnexin and calregulin (also called calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum, Calnexin to the membrane and calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor calregulin contains the calcium-binding "E-F hand" motif found in calmodulins. Calnexin and calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: Calreticulin monoclonal Antibody detects endogenous levels of Calreticulin protein.

Molecular Weight: 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ERp60, CALR, CRTC, Autoantigen RO, CALR, CALR protein, CALR, Calregulin, Calreticulin, cC1qR, CRP55, CRT, CRTC, Endoplasmic reticulum resident protein 60, Epididymis secretory sperm binding protein Li 99n, ERp60, FLJ26680, grp60, HACBP, HEL S 99n, RO, Sicca syndrome antigen A (autoantigen Ro; calreticulin), Sicca syndrome antigen A, SSA,

Immunogen: Recombinant protein.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProG affinity purified.

Pathway: