Calsequestrin 1 polyclonal Antibody | BS90175

Calsequestrin 1 polyclonal Antibody | BS90175 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC FC

Application Range: WB:1:500 IHC:1:50-1:200 FC:1:50-1:100

Background: Calsequestrin (CS, also known as CSQ) is the major calcium-binding protein of cardiac and skeletal muscle whose function is to sequester calcium in the lumen of the sarcoplasmic reticulum (SR) . In mammals, there are two forms of this protein, calsequestrin 1 and calsequestrin 2, which encode fast-twitch skeletal muscle and cardiac calsequestrin, respectively. Calsequestrin 1, also known as Calmitin, is located in the terminal cisternae luminal spaces of the SR of fast skeletal muscle cells. Calsequestrin 2 is present in terminal cisternae luminal spaces of the SR of both cardiac and slow skeletal muscle cells. In addition, calsequestrin regulates the ryanodine receptor signaling (RyR) through Triadin and Junctin.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Calsequestrin 1 polyclonal Antibody detects endogenous levels of Calsequestrin 1 protein.

Molecular Weight: 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CASQ1, CASQ, Calmitin, Calmitine, Calsequestrin 1 (fast twitch, skeletal muscle), Calsequestrin, Calsequestrin, cell, Calsequestrin, skeletal muscle isoform, Calsequestrin-1, CASQ, Casq1, CASQ1, PDIB1, skeletal muscle isoform,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: