Calyculin A | 1562

Calyculin A is a very potent inhibitor (Ki = 0.1 nM) with high specificity for the PP-1 and PP-2 classes of protein serine/threonine phosphatase. It is also a potent non-phorbol type tumor promoter.

Calyculin A is a very potent inhibitor (Ki = 0.1 nM) with high specificity for the PP-1 and PP-2 classes of protein serine/threonine phosphatase. It is also a potent non-phorbol type tumor promoter.

1562 | Calyculin A DataSheet

Alternate Name/Synonyms:

Appearance: White solid

Formulation: N/A

CAS Number: 101932-71-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅₀H₈₁N₄O₁₅P

Molecular Weight: 1009.17

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO or EtOH

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A protein phosphatsae inhibitor

MDL Number: MFCD06795864

PubChem CID: 2534

SMILES: CC1C(CC2(C(C(C(O2)C(CC(C(C)C(C(C)C=C(C)C(=CC=CC(=CC#N)C)C)O)O)OC)OP(=O)(O)O)(C)C)OC1CC=CC3=COC(=N3)C(C)CCNC(=O)C(C(C(COC)N(C)C)O)O)O

InChi: InChI=1S/C50H81N4O15P/c1-29(20-22-51)16-14-17-30(2)32(4)24-33(5)42(57)35 (7)38(55)25-41(65-13)45-46(69-70(61,62)63)49(8, 9)50(68-45)26-39(56)34(6)40(67-50)19-15-18-36-27-66-48(53-36)31(3)21-23- 52-47(60)44(59)43(58)37(28-64-12)54(10)11/h14-18,20,24,27,31,33-35, 37-46,55-59H,19,21,23,25-26,28H2,1-13H3,(H,52,60)(H2,61,62,63)

InChi Key: FKAWLXNLHHIHLA-UHFFFAOYSA-N