CAPN2 Antibody (N-Term) [APG02360G]

CAPN2 Antibody (N-Term) [APG02360G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M, Rat

Specificity: This CAPN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 10-43 amino acids from human CAPN2.

Cellular Localisation: Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca (2+) binding

Molecular Weight: 79995

Clone: Polyclonal

Gene Name: CAPN2

Gene ID: 824

Function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508) . Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity) .

Summary: Tissue Location: Ubiquitous.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:8000

Synonyms: Calpain-2 catalytic subunit, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, M-calpain, CAPN2, CANPL2