CAPRIN1 Polyclonal Antibody | E-AB-62119

CAPRIN1 Polyclonal Antibody | E-AB-62119 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CAPRIN1, GPIAP1, GPIP137, GRIP137, M11S1, RNG105, p137GPI, caprin-1

Application: WB, IHC

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology

Background: Caprin-1is aproteinthat in humans is encoded by theCAPRIN1gene. May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human CAPRIN1

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:100-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 76 kDa/78 kDa

Molecular Weight(Observed): 120 kDa