Carbamazepine | B2401

Carbamazepine is an inhibitor of neuronal voltage-gated Na+ channels. It displays anticonvulsant activity and potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor α1β2γ2 subtype combination. Can induce autophagy by inhibiting inositol synthesis. Also acts as an in vitro inducer of CYP3A4, the main human metabolizing enzyme present in the liver and intestine.

Carbamazepine is an inhibitor of neuronal voltage-gated Na+ channels. It displays anticonvulsant activity and potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor α1β2γ2 subtype combination. Can induce autophagy by inhibiting inositol synthesis. Also acts as an in vitro inducer of CYP3A4, the main human metabolizing enzyme present in the liver and intestine.

B2401 | Carbamazepine DataSheet

Alternate Name/Synonyms: 5H-Dibenz[b,f]azepine-5-carboxamide, CBZ

Appearance: White solid

Formulation:

CAS Number: 298-46-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₂N₂O

Molecular Weight: 236.27

Cell-Permeable?: False

Purity: ≥98% by HPLC

Solubilities: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: Inhibitor of neuronal NaV channels

MDL Number: MFCD00005073

PubChem CID: 2554

SMILES: C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N

InChi: InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)

InChi Key: FFGPTBGBLSHEPO-UHFFFAOYSA-N