CASP7 Polyclonal Antibody | E-AB-30758

CASP7 Polyclonal Antibody | E-AB-30758 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Apoptotic protease Mch-3, Apoptotic protease MCH3, CASP-7, CASP7, CASP7, Caspase 7, Caspase 7 apoptosis related cysteine peptidase, Caspase-7 subunit p11, Caspase7, CMH 1, CMH-1, CMH1, ICE LAP3, ICE-LAP3, ICE-like apoptotic protease 3, LICE2, MCH3

Application: WB, IHC-p, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Metabolism

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from the N-terminal region of human Caspase-7.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ICC 1:200-1:1000, ELISA 1:5000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 34 kDa

Molecular Weight(Observed): 35 kDa