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Caspase-13 Inhibitor LEED-FMK | 1115

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SKU:
26-1115-GEN
Availability:
Usually shipped in 5 working days
NULL388.00

Description

A synthetic peptide inhibitor that inhibits caspase-13 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Z-LEED-FMK is a cell-permeable, irreversible caspase-13 inhibitor.

1115 | Caspase-13 Inhibitor LEED-FMK DataSheet

Alternate Name/Synonyms: Z-LEED-FMK, Z-LEED-fluoromethylketone, Caspase-13 Inhibitor (fluoromethylketone)

Appearance: Liquid

Formulation: DMSO (2 mM)

CAS Number: N/A

Structure Available?: No

Peptide sequence: Z-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-FMK

Salt Form: No

Molecular Formula: C₃₂H₄₅FN₄O₁₂

Molecular Weight: 696.7

Cell-Permeable?: Yes

Purity: >95% by HPLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A caspase-13 inhibitor

MDL Number: MFCD03453602

PubChem CID: 44135223

SMILES: CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CCC(=O)OC)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1

InChi: InChI=1S/C32H45FN4O12/c1-19(2)15-24(37-32(45)49-18-20-9-7-6-8-10-20)31(44)35-21(11-13-26(39)46-3)29(42)34-22(12-14-27(40)47-4)30(43)36-23(25(38)17-33)16-28(41)48-5/h6-10,19,21-24H,11-18H2,1-5H3,(H,34,42)(H,35,44)(H,36,43)(H,37,45)

InChi Key: JQWJGEBRHHCICO-UHFFFAOYSA-N

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Additional Information

Storage Condition:
-20°C
Shipping Condition:
Gel Pack
Shelf Life:
12 months
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