BW
Caspase 14 polyclonal Antibody | BS8531
- SKU:
- BW-BS8531
- Availability:
- Usually ships in 5 working days
Description
Caspase 14 polyclonal Antibody | BS8531 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IF
Application Range: WB 1:500 - 1:2000 IF 1:10 - 1:100
Background: Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p19 and p10 subunits by caspase-8. Caspase-14 may not play a role in apoptosis, but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Caspase 14 polyclonal Antibody detects endogenous levels of Caspase 14 protein.
Molecular Weight: ~ 27kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Caspase14; Caspase-14; CASP-14; Caspase-14 subunit p10; CASP14
Immunogen: Recombinant full length Human Caspase 14.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: