Caspase-2 Assay Kit (Colorimetric) | KTA3021

Caspase-2 Assay Kit (Colorimetric) | KTA3021 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cellular states

Product Type: Apoptosis Detection Kit

Sequence: N/A

Activity: N/A

protein Lenght: N/A

Preparation: N/A

Purity: N/A

Formulation: N/A

Kit Component: • Cell Lysis Buffer
• Reaction Buffer (2×)
• Ac-DEVD-pNA (4mM)
• pNA (10mM)
• DTT (100×)

Features & Benefits : • Simple and optimized procedure.
• Fast and convenient.
• Detect early/middle stages of apoptosis.

Molecular Weight: N/A

Usage Note: N/A

Storage Conditions: Stable for at least 12 months at recommended temperature from date of shipment. Gel pack with blue ice.

Shipping: Gel pack with blue ice.

Background: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Mammalian caspases can be subdivided into three functional groups: initiator caspases (Caspase 2, 8, 9 and 10), executioner caspases (Caspase-3, 6 and 7), and inflammatory caspases (Caspase 1, 4, 5, 11 and 12) . Caspase-3, also known as Yama, CPP32, and apopain, cleaves its substrates at the carboxyl terminus of aspartate residues. Active Caspase-3 consists of 2 sets of homodimers (17 and 12 kDa) that are derived from two precursor Caspase-3 polypeptides and has two active sites. Caspase-3, together with Caspases 8 and 9, is situated at pivotal junctions in apoptotic pathways.

Alternative Names: N/A

Search Names: N/A

Tag: Caspase