Caspase 4 (E124) polyclonal Antibody | BS3686

Caspase 4 (E124) polyclonal Antibody | BS3686 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: IHC: 1:50~1:200

Background: A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly (ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Caspase-4 (E124) polyclonal Antibody detects endogenous levels of Caspase-4 protein.

Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Caspase-4; CASP-4; ICE (rel) -II; Protease ICH-2; Protease TX; Caspase-4 subunit 1; CASP4; ICH2; Caspase 4; Caspase4

Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human Caspase 4.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: