Caspase-5 Substrate WEHD-pNA | 1102

Ready-to-use colorimetric substrate for caspase-5 and related caspases that recognize the amino acid sequence WEHD. Caspase-5 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleaved from the peptide substrate WEHD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large volume of caspase assays.

WEHD-pNA is a ready-to-use fluorometric substrate for caspase-1,-4,-5 and related caspases that recognize the amino acid sequence WEHD.

1102 | Caspase-5 Substrate WEHD-pNA DataSheet

Alternate Name/Synonyms: Ac-WEHD-pNA, Caspase-5 Substrate, Colorimetric

Appearance: Liquid

Formulation: DMSO (4 mM)

CAS Number: N/A

Structure Available?: No

Peptide sequence: Ac-Trp-Glu-His-Asp-pNA

Salt Form: No

Molecular Formula: C₃₄H₃₇N₉O₁₁

Molecular Weight: 747.7

Cell-Permeable?: No

Purity: >99% by HPLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A caspase-5 substrate

MDL Number: N/A

PubChem CID: 44135315

SMILES: CC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CN=CN3)C(=O)NC(CC(=O)O)C(=O)NC4=CC=C(C=C4)[N+](=O)[O-]

InChi: InChI=1S/C34H37N9O11/c1-18(44)38-26(12-19-15-36-24-5-3-2-4-23(19)24)33(51)40-25(10-11-29(45)46)31(49)41-27(13-21-16-35-17-37-21)34(52)42-28(14-30(47)48)32(50)39-20-6-8-22(9-7-20)43(53)54/h2-9,15-17,25-28,36H,10-14H2,1H3,(H,35,37)(H,38,44)(H,39,50)(H,40,51)(H,41,49)(H,42,52)(H,45,46)(H,47,48)

InChi Key: FDGCMTAKGVLJGO-UHFFFAOYSA-N