Casticin | B1575

Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis. It displays anticancer activities including induction of cell apoptosis in human cancer cells. Casticin impairs cell migration and invasion of mouse melanoma B16F10 cells via PI3K/AKT and NF-κB signaling pathways.

Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis. It displays anticancer activities including induction of cell apoptosis in human cancer cells. Casticin impairs cell migration and invasion of mouse melanoma B16F10 cells via PI3K/AKT and NF-κB signaling pathways.

B1575 | Casticin DataSheet

Alternate Name/Synonyms: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one; Vitexicarpin

Appearance: Yellow solid

Formulation: N/A

CAS Number: 479-91-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₉H₁₈O₈

Molecular Weight: 374.34

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (10 mg/ml) or EtOH (1 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An anticancer agent

MDL Number: MFCD00210481

PubChem CID: 5315263

SMILES: COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC)O

InChi: InChI=1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3

InChi Key: PJQLSMYMOKWUJG-UHFFFAOYSA-N