Catenin delta 1 (Phospho-Y228) polyclonal Antibody | BS64524

Catenin delta 1 (Phospho-Y228) polyclonal Antibody | BS64524 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC IF

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: The α, β, δ, and γ -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. δ-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding δ-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding δ-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. γ-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds α-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Catenin delta 1 (Phospho-Y228)  polyclonal Antibody detects endogenous levels of Catenin delta 1 protein only when phosphorylated at Tyr228.

Molecular Weight: ~ 108 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Catenin δ1; Catenin delta-1; Cadherin-associated Src substrate; Short name=CAS; p120 catenin; p120 (ctn) ; p120 (cas) ; CTNND1; KIAA0384

Immunogen: Synthetic phosphopeptide derived from human Catenin delta 1 around the phosphorylation site of Tyrosine 228.

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: