Catharanthine | 1749

Catharanthine is one of the alkaloids isolated from the plant Catharanthus roseus. It stimulates the release of amylase from pancreatic fragments and causes extensive degranulation of pancreatic acinar cells with accumulation of membrane material in the Golgi region. It also fully inhibits nicotinic receptor mediated diaphragm contractions (IC₅₀ = 59.6 µM).

Catharanthine is one of the alkaloids isolated from the plant Catharanthus roseus. It stimulates the release of amylase from pancreatic fragments and causes extensive degranulation of pancreatic acinar cells with accumulation of membrane material in the Golgi region.

1749 | Catharanthine DataSheet

Alternate Name/Synonyms: Methyl (2ɑ,5β,6 ɑ)-3,4-didehydroibogamine-18 β -carboxylate ; 6,9-Methano-5H-pyrido[1',2':1,2]azepino[4,5-b]indole

Appearance: White crystalline solid

Formulation: N/A

CAS Number: 2468-21-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₄N₂O₂

Molecular Weight: 336.43

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A plant alkalod

MDL Number: MFCD01753356

PubChem CID: 418553

SMILES: CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC

InChi: InChI=1S/C21H24N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,10,13,19,22H,3,8-9,11-12H2,1-2H3

InChi Key: CMKFQVZJOWHHDV-UHFFFAOYSA-N