Cathepsin F, human recombinant | 9232

Cathepsin F, also known as CTSF, belongs to the cathepsin family. Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. The CTSF gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. CTSF is thought to play a role in normal protein catabolism, and because it is highly expressed in some cancer cell lines, it may be involved in degradative processes occurring during tumor progression. Recombinant human CTSF protein, fused to His-tag at N-terminus, was expressed in E.coli.

9232 | Cathepsin F human recombinant DataSheet

Biomolecule/Target: CTSF

Synonyms: CATSF, CLN13, CTSF

Alternates names: Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein,Prostate differentiation factor

Taglines: Protease involved in intracellular degradation and turnover of proteins.

NCBI Gene ID #: 9518

NCBI Gene Symbol: GDF-15

Gene Source: Human

Accession #: Q99988

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: 90%

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity:

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 12.4 kDa (monomer), 24.8 kDa (dimer)

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: Liquid

Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile deionized water or a solution of 5 mM acetic acid at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.             

Amino acid sequence: MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI