Cathepsin G, Human Neutrophil | 4713

Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.

4713 | Cathepsin G Human Neutrophil DataSheet

Biomolecule/Target: N/A

Synonyms: Cathepsin G

Alternates names: Cathepsin G, CTSG

Taglines: Involved in connective tissue remodeling at sites of inflammation

NCBI Gene ID #: 5909

NCBI Gene Symbol: RARRES2

Gene Source: N/A

Accession #: Q99969

Recombinant: No

Source: Human Neutrophil

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): 2 to 4 units per mg protein. One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-Ala-Ala-Pro-Phe-pNA (1 mM) per minute at 25°C in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 23.5 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Salt- free lyophilized solid

Reconstitution Instructions: Deionized HO

Amino acid sequence: N/A