Cathepsin L Polyclonal Antibody | E-AB-10211

Cathepsin L Polyclonal Antibody | E-AB-10211 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: cathepsin L, 1 b, Cathepsin L1, Cathepsin L1 light chain, CathepsinL, CATL, CATL1, cb15, CTSL, CTSL1, ctsl1b, FLJ31037, hgg1, Major excreted protein, MEP, MGC123162, wu:fb30g09

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience, Signal Transduction

Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human CTSL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A