CAV3 Polyclonal Antibody | E-AB-13049

CAV3 Polyclonal Antibody | E-AB-13049 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CAV3, CAV3, Caveolin 3, Caveolin-3, LGMD1C, LQT9, M-caveolin, MGC126100, MGC126101, MGC126129, OTTHUMP00000115603, OTTHUMP00000207105, VIP 21, VIP21

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction, Tags and Cell Markers

Background: This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human CAV3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 17 kDa

Molecular Weight(Observed): N/A