Description
CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor). The IC₅₀ for inhibition of PCAF is 662 μM. CAY10669 at 30-60 μM concentration dose-dependently inhibits histone H4 acetylation in HepG2 cells.
CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor). The IC₅₀ for inhibition of PCAF is 662 μM. CAY10669 at 30-60 μM concentration dose-dependently inhibits histone H4 acetylation in HepG2 cells.
Alternate Name/Synonyms: (Z)-2-Hydroxy-6-(4-(pentyloxy)styryl)benzoic acid, 2-hydroxy-6-[(1Z)-2-[4-(pentyloxy)phenyl]ethenyl]-benzoicacid
Appearance: Crystalline solid
Formulation:
CAS Number: 1243583-88-1
Structure Available?: True
Peptide sequence:
Salt Form: False
Molecular Formula: C₂₀H₂₂O₄
Molecular Weight: 326.39
Cell-Permeable?: True
Purity: ≥98%
Solubilities: 30 mg/ml in ethanol, DMSO and DMF in 0
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: It is an inhibitor of the histone acetyltransferase PCAF
MDL Number:
PubChem CID: 46927927
SMILES: CCCCCOC1=CC=C(C=C1)C=CC2=C(C(=CC=C2)O)C(=O)O
InChi: InChI=1S/C20H22O4/c1-2-3-4-14-24-17-12-9-15(10-13-17)8-11-16-6-5-7-18(21)19(16)20(22)23/h5-13,21H,2-4,14H2,1H3,(H,22,23)/b11-8-
InChi Key: JZTUSBQKQHUSQE-FLIBITNWSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |