CB-103 | B3256

CB-103 acts as a potent Pan-NOTCH inhibitor by targeting NOTCH transcriptional activation complex. CB-103 blocks NOTCH signaling in human T cell acute lymphoblastic leukemia cancer cell lines and displays anti-tumor efficacy in GSI resistant T-ALL cell lines.

CB-103 acts as a potent Pan-NOTCH inhibitor by targeting NOTCH transcriptional activation complex. CB-103 blocks NOTCH signaling in human T cell acute lymphoblastic leukemia cancer cell lines and displays anti-tumor efficacy in GSI resistant T-ALL cell lines.

B3256 | CB-103 DataSheet

Alternate Name/Synonyms: 5-Amino-2-(4-tert-butylphenoxy)pyridine 6-(4-tert-butylphenoxy)pyridin-3-amine

Appearance: Crystalline solid

Formulation:

CAS Number: 218457-67-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₈N₂O

Molecular Weight: 242.32

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent Notch inhibitor

MDL Number:

PubChem CID: 2735289

SMILES: CC(C)(C)C1=CC=C(C=C1)OC2=NC=C(C=C2)N

InChi: InChI=1S/C15H18N2O/c1-15(2,3)11-4-7-13(8-5-11)18-14-9-6-12(16)10-17-14/h4-10H,16H2,1-3H3

InChi Key: WHIWGRCYMQLLAO-UHFFFAOYSA-N